Description: The percentage of the population who are obese has grown dramatically worldwide over the last several decades, although stabilizing recently in the United States. Studies have found the effects on mortality to be inconsistent and controversial because of methodological differences and the complexity of the relationship between obesity and mortality. This paper discusses this relationship and sheds light on the likely effects of this epidemic. Issues associated with the so-called obesity-mortality paradox, where mortality experience is lower for those individuals who are overweight and in some who are obese compared with the mortality of those in the normal weight category, are examined. Although certain recently reported studies of the relationship between mortality and obesity indicate that obesity is related to a reduced percent of additional mortality, this may in part be due to the shorter average time that those currently obese have been exposed to their condition. Nevertheless, the amount of health care costs and rates of disability associated with being obese are significant, contributing to the increase in overall health care costs as they become more numerous and age. Although obesity is being addressed with a great deal of activity and publicity, they will continue to prove challenging for individuals and society to manage and overcome.